UROLOGIC ONCOLOGY · ROBOTIC SURGERY · MIAMI
Dr. Archan Khandekar
Fellowship-trained urologic cancer surgeon specializing in robotic surgery, image-guided prostate biopsy, and organ-sparing treatment for prostate, bladder, and kidney cancer.
Assistant Professor of Urologic Oncology · Desai Sethi Urology Institute
University of Miami · Sylvester Comprehensive Cancer Center
156 patient ratings · 20 reviews
- Likelihood to recommend
- 4.9
- Explained things clearly
- 4.9
- Courtesy and respect
- 4.9
- Listened carefully
- 4.9
- Spent enough time
- 4.8
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Surgery Built Around Precision and Recovery
Dr. Khandekar cares for the full range of urologic cancers, with particular depth in robotic surgery and advanced, image-guided prostate biopsy. Every plan is built to control the cancer while protecting the things that matter to daily life.
Robotic & Minimally Invasive Surgery
Fellowship-trained robotic surgery across the urologic cancers, using the da Vinci platform to remove tumors precisely while sparing healthy tissue, shortening recovery, and preserving urinary and sexual function.
- Robotic-assisted radical prostatectomy
- Robotic partial nephrectomy (kidney-sparing)
- Robotic radical nephrectomy
- Robotic radical cystectomy with urinary diversion
- Transurethral resection of bladder tumor (TURBT)
- Bladder cancer surgery and reconstruction
Image-Guided Prostate Biopsy
A full range of prostate biopsy techniques, from the newest augmented-reality guidance to MRI-fusion and standard sampling, chosen to find clinically significant cancer while avoiding unnecessary treatment.
- Augmented-reality guided prostate biopsy
- MRI–ultrasound fusion (targeted) biopsy
- Standard systematic biopsy
- Transperineal and transrectal approaches
Focal Therapy & Precision Oncology
Treatments that control cancer while protecting quality of life, guided by genomics and advanced imaging so the intensity of treatment matches the biology of the disease.
- HIFU focal therapy for localized prostate cancer
- Genomic and MRI-guided treatment selection
- Nerve-sparing, function-preserving surgery
- Multidisciplinary cancer care and survivorship
Research & Innovation
Advancing How Cancer Surgery Is Done
Alongside his practice, Dr. Khandekar develops the artificial intelligence, augmented reality, and genomic tools that are reshaping urologic care, published across the peer-reviewed literature.
Artificial Intelligence in Urology
Development of AI models for surgical decision support, including automated surgical metric measurement and computer vision for intraoperative guidance.
Augmented Reality in Surgery & Outpatient Care
AR-guided biopsies, AR applications in clinical interventions, and evaluation of AR systems in outpatient urological settings.
Genomic Biomarkers & Active Surveillance
Validation of Decipher, PAM50, and PSC genomic classifiers for predicting progression in prostate cancer active surveillance, through the Miami Active Surveillance Trial (MAST).
Surgical Intelligence & Computer Vision
HL7 integration, intraoperative data analytics, automated warm ischemia time measurement, and surgical performance assessment.
Selected Publications
Recent peer-reviewed work.
Prediction Analysis of Microarray of 50 genes (PAM50) classifier validated for predicting prostate cancer progression in active surveillance: Miami Active Surveillance Trial (MAST)
BJU Int. 2026
Read paper →Concordance among experts in assessing apical mucosal preservation during holmium laser enucleation of the prostate (HoLEP): implications for artificial intelligence model development
World J Urol. 2025;44(1):20
Read paper →Augmented Reality in Outpatient Care: A Narrative Review
Healthc Technol Lett. 2025;12(1):e70025
Read paper →4K density: Adjusting the 4Kscore for prostate volume to improve risk stratification of clinically significant prostate cancer in men undergoing prostate biopsy
Prostate Cancer Prostatic Dis. 2025
Read paper →Schedule a Consultation
Dr. Khandekar sees patients across the University of Miami Health System and Sylvester Comprehensive Cancer Center. Request an appointment for urologic oncology care.